Nodal status matters

More differentiated information – Supporting better treatment decisions Lymph node status is one of the most important prognostic factors in many cancers and a key criterion for surgical and therapeutic decisions. Analysing lymph node tissue reliably and accuracy is therefore crucial for detecting metastases. Routine practice in histopathology analyses only a limited amount of tissue and therefore provides only limited information, which might not reflect the real metastatic burden. OSNA – One Step Nucleic Acid Amplification – is an automated molecular diagnostic assay that analyses the entire lymph node tissue. The reaction is based on rapid nucleic acid amplification technology (RT-LAMP*) to quantify Cytokeratin 19 (CK19) mRNA